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Article

Characterization of Siglec-5, a Novel Glycoprotein Expressed on Myeloid Cells Related to CD33

15 Sept 1998

Abstract excerpt

We describe the characterization of siglec-5 (sialic acid-binding Ig-like lectin-5), a novel transmembrane member of the immunoglobulin superfamily, highly related to the myeloid antigen, CD33. A full-length cDNA encoding siglec-5 was isolated from a human activated monocyte cDNA library. Sequencing predicted that siglec-5 contains four extracellular immunoglobulin-like domains, the N-terminal two of which are...

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Identifiers

PMID: 9731071
DOI: 10.1182/blood.v92.6.2123

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