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Article

Mechanism for specificity by HMG-1 in enhanceosome assembly.

Molecular and cellular biology - 1 Jun 2000

Ellwood K B, Yen Y M, Johnson R C, Carey M

Abstract excerpt

Assembly of enhanceosomes requires architectural proteins to facilitate the DNA conformational changes accompanying cooperative binding of activators to a regulatory sequence. The architectural protein HMG-1 has been proposed to bind DNA in a sequence-independent manner, yet, paradoxically, it facilitates specific DNA binding reactions in vitro. To investigate the mechanism of specificity we explored the effect...

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Identifiers

PMID: 10825199
DOI: 10.1128/MCB.20.12.4359-4370.2000
PMCID: PMC85803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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