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Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells

1 Jun 2017

Abstract excerpt

Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable variability, particularly when applied to pluripotent cells from diverse genetic backgrounds. We have developed culture conditions that support long-term self-renewal of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28591650
DOI: 10.1016/j.stemcr.2017.05.019

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