Article
Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis.
Stem cells (Dayton, Ohio) - 1 Sept 2013
Wang Yunfang, Lanzoni Giacomo, Carpino Guido, Cui Cai-Bin, Dominguez-Bendala Juan, Wauthier Eliane, Cardinale Vincenzo, Oikawa Tsunekazu, Pileggi Antonello, Gerber David, Furth Mark E, Alvaro Domenico, Gaudio Eugenio, Inverardi Luca, Reid Lola M
Abstract excerpt
Peribiliary glands (PBGs) in bile duct walls, and pancreatic duct glands (PDGs) associated with pancreatic ducts, in humans of all ages, contain a continuous, ramifying network of cells in overlapping maturational lineages. We show that proximal (PBGs)-to-distal (PDGs) maturational lineages start near the duodenum with cells expressing markers of pluripotency (NANOG, OCT4, and SOX2), proliferation (Ki67),...
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