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Article

A two-step culture method starting with early growth factors permits enhanced production of functional dendritic cells from murine splenocytes.

Journal of immunological methods - 26 May 2000

Berthier R, Martinon-Ego C, Laharie A M, Marche P N

Abstract excerpt

Dendritic cells (DC) are professional antigen presenting cells (APC) able to activate naive T cells and initiate the immune response. They are present in most tissues at very low concentrations and are difficult to isolate. DC can be obtained in larger numbers by their propagation from progenitors present in blood, bone marrow and spleen. However, biochemical studies and biological analysis of DC functions...

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PMID: 10821951
DOI: 10.1016/s0022-1759(00)00186-1

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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