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Article

The ryanodine receptor is essential for larval development in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America - 23 May 2000

Sullivan K M, Scott K, Zuker C S, Rubin G M

Abstract excerpt

We have investigated the role of the ryanodine receptor in Drosophila development by using pharmacological and genetic approaches. We identified a P element insertion in the Drosophila ryanodine receptor gene, Ryanodine receptor 44F (Ryr), and used it to generate the hypomorphic allele Ryr(16). An examination of hypodermal, visceral, and circulatory muscle showed that, in each case, muscle contraction was...

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Identifiers

PMID: 10811919
DOI: 10.1073/pnas.110145997
PMCID: PMC18538

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Source receipt: pubmed, retrieved 7 Sept 2026.

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