Article
Expression from the human occludin promoter is affected by tumor necrosis factor α and interferon γ
1 Jun 2000
Abstract excerpt
The 65 kDa protein occludin is a membrane-spanning part of the epithelial tight junction, which is the main barrier of the paracellular pathway. The function of occludin as part of tight junctions is still poorly understood and even less is known about the regulatory mechanisms that influence occludin gene expression. This study aimed to identify the sequences essential in cis for genomic regulation of tight...
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