Article
Molecular genetic methods in the diagnosis of myelodysplastic syndromes. A review.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Sept 2014
Lukackova Renata, Gerykova Bujalkova Maria, Majerova Lubica, Mladosievicova Beata
Abstract excerpt
BACKGROUND: Myelodysplastic syndromes (MDS) represent a heterogeneous group of premalignant hematologic disorders characterized by ineffective hematopoiesis, peripheral blood cytopenias and increased risk of progression to acute leukemia. Cytogenetic analysis still plays a central role in the diagnosis of MDS, as clonal chromosomal abnormalities are observed in 30-50% of MDS patients. Despite their technical...
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