Article
Myelodysplastic syndrome: review of the cytogenetic and molecular data.
Critical reviews in oncology/hematology - 1 Dec 2001
Mhawech P, Saleem A
Abstract excerpt
Myelodysplastic syndrome (MDS) is a monoclonal disorder of the pluripotent stem cell that frequently evolves into acute leukemia. MDS is characterized by trilineage dysplasia and by ineffective hematopoiesis. The etiology of MDS is poorly understood. However, the frequent association of chromosomal abnormalities (deletions, inversions, translocations, trisomies and monosomies) with MDS suggests that an oncogene,...
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