Article
RNA motifs that determine specificity between a viral replicase and its promoter.
Nature structural biology - 1 May 2000
Kim C H, Kao C C, Tinoco I
Abstract excerpt
The 3' end of brome mosaic virus RNA contains a tRNA-like sequence that directs its RNA synthesis. A stem loop structure in this sequence, stem loop C (SLC), was investigated using NMR, and correlated with its ability to direct RNA synthesis by its replicase. SLC consists of two discrete domains, a flexible stem with an internal loop and a rigid stem containing a 5'-AUA-3' triloop. Efficient RNA synthesis...
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