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Article

A local, interactive network of 3' RNA elements supports translation and replication of Turnip crinkle virus.

Journal of virology - 1 Apr 2012

Yuan Xuefeng, Shi Kerong, Simon Anne E

Abstract excerpt

The majority of the 3' untranslated region (UTR) of Turnip crinkle virus (TCV) was previously identified as forming a highly interactive structure with a ribosome-binding tRNA-shaped structure (TSS) acting as a scaffold and undergoing a widespread conformational shift upon binding to RNA-dependent RNA polymerase (RdRp). Tertiary interactions in the region were explored by identifying two highly detrimental...

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Identifiers

PMID: 22345459
DOI: 10.1128/JVI.07019-11
PMCID: PMC3318645

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