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Article

Gene expression and neuroblastoma cell differentiation in response to retinoic acid: differential effects of 9-cis and all-trans retinoic acid.

European journal of cancer (Oxford, England : 1990) - 1 Jan 1995

Redfern C P, Lovat P E, Malcolm A J, Pearson A D

Abstract excerpt

Retinoic acid has considerable potential for the chemoprevention and chemotherapy of cancer. Neuroblastoma cells differentiate in response to retinoic acid in vitro, an observation that has led to clinical trials using either the 13-cis or all-trans isomers of retinoic acid. We review the effects...

Topics

Antineoplastic Agents
Cell Differentiation
Cell Division
Gene Expression Regulation, Neoplastic
Humans
Neuroblastoma
Phenotype
Tretinoin
Tumor Cells, Cultured

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7576951
DOI: 10.1016/0959-8049(95)00066-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7576951-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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