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Article

Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae.

Molecular biology of the cell - 1 May 2000

Karpova T S, Reck-Peterson S L, Elkind N B, Mooseker M S, Novick P J, Cooper J A

Abstract excerpt

We examined the role of the actin cytoskeleton in secretion in Saccharomyces cerevisiae with the use of several quantitative assays, including time-lapse video microscopy of cell surface growth in individual living cells. In latrunculin, which depolymerizes filamentous actin, cell surface growth was completely depolarized but still occurred, albeit at a reduced level. Thus, filamentous actin is necessary for...

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Identifiers

PMID: 10793147
DOI: 10.1091/mbc.11.5.1727
PMCID: PMC14879

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