Article
Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa.
Journal of bacteriology - 1 Oct 1995
Schurr M J, Yu H, Boucher J C, Hibler N S, Deretic V
Abstract excerpt
Overproduction of the exopolysaccharide alginate causes mucoid colony morphology in Pseudomonas aeruginosa and is considered a major virulence determinant expressed by this organism during chronic respiratory infections in cystic fibrosis. One of the principal regulatory elements governing conver...
Topics
- Alginates
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cystic Fibrosis
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Glucuronic Acid
- Heat-Shock Response
- Hexuronic Acids
- Molecular Sequence Data
- Osmolar Concentration
- Phenotype
- Promoter Regions, Genetic