Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation.

Abstract excerpt

Tight junctions are intercellular junctions localized at the most apical end of the lateral plasma membrane. They consist of four kinds of transmembrane proteins (occludin, claudins, junctional adhesion molecules, and tricellulin) and huge numbers of scaffolding proteins and contribute to the paracellular barrier and fence function. The mutation and deletion of these proteins impair the functions of tight...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Adhesion Molecules
• Share to Claudins