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Article

Modification of wild-type and batrachotoxin-resistant muscle mu1 Na+ channels by veratridine.

Pflugers Archiv : European journal of physiology - 1 Apr 2000

Wang G K, Quan C, Seaver M, Wang S Y

Abstract excerpt

Biochemical evidence indicates that veratridine (VTD) and batrachotoxin (BTX) share a common binding site in Na+ channels. Under whole-cell voltage-clamp conditions, we examined this single receptor hypothesis by studying the VTD phenotype in BTX-resistant muscle Na+ channels, microl-I433K, N434K, L437K, F1579K, and N1584K. Derived from point mutations at segments D1-S6 and D4-S6, these mutant Na+ channels are...

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PMID: 10784344
DOI: 10.1007/s004249900229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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