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Article

Influence of apolipoprotein E genotype on the risk of cognitive deterioration in moderate drinkers and smokers.

Epidemiology (Cambridge, Mass.) - 1 May 2000

Dufouil C, Tzourio C, Brayne C, Berr C, Amouyel P, Alpérovitch A

Abstract excerpt

We investigated the risk of cognitive deterioration in relation to alcohol consumption and smoking according to the apolipoprotein E (ApoE) polymorphism. The ApoE epsilon4 allele is an established risk factor for dementia and cognitive impairment. There are also some recent indications that vascular risk factors, including alcohol and tobacco consumption, might play a role in cognition. Our data are from the...

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Source

Identifiers

PMID: 10784244
DOI: 10.1097/00001648-200005000-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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