Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasticity in the organization and sequences of human KIR/ILT gene families.

Proceedings of the National Academy of Sciences of the United States of America - 25 Apr 2000

Wilson M J, Torkar M, Haude A, Milne S, Jones T, Sheer D, Beck S, Trowsdale J

Abstract excerpt

The approximately 1-Mb leukocyte receptor complex at 19q13.4 is a key polymorphic immunoregion containing all of the natural killer-receptor KIR and related ILT genes. When the organization of the leukocyte receptor complex was compared from two haplotypes, the gene content in the KIR region varied dramatically, with framework loci flanking regions of widely variable gene content. The ILT genes were more stable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alu Elements
Share to Chromosomes, Human, Pair 19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Killer Cells, Natural

Share to Microsatellite Repeats

Share to Multigene Family

Share to Receptors, Immunologic

Share to Receptors, KIR

Source

Open in PubMed Open full text

Identifiers

PMID: 10781084
DOI: 10.1073/pnas.080588597
PMCID: PMC18309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasticity in the organization and sequences of human KIR/ILT gene families.PMID 10781084Read ↗

The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster.Semantic proximity Read ↗

Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family.Semantic proximity Read ↗

Revealing Complete Complex <i>KIR</i> Haplotypes Phased by Long-read Sequencing TechnologySemantic proximity Read ↗

Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates.Semantic proximity Read ↗

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors.Semantic proximity Read ↗

The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates.Semantic proximity Read ↗

Genesis of the ILT/LIR/MIR clusters within the human leukocyte receptor complex.Semantic proximity Read ↗

The KIR gene family: life in the fast lane of evolution.Semantic proximity Read ↗

Arrangement of the ILT gene cluster: a common null allele of the ILT6 gene results from a 6.7-kbp deletion.Semantic proximity Read ↗

A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-based Multiple Sequence AlignmentSemantic proximity Read ↗

Genetic Diversity and Structural Complexity of the Killer-Cell Immunoglobulin-Like Receptor Gene Complex: A Comprehensive Analysis Using Human Pangenome AssembliesSemantic proximity Read ↗

Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.