Article
Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning.
The Journal of biological chemistry - 30 Jun 2000
Ariizumi K, Shen G L, Shikano S, Xu S, Ritter R, Kumamoto T, Edelbaum D, Morita A, Bergstresser P R, Takashima A
Abstract excerpt
Dendritic cells (DC) are special subsets of antigen presenting cells characterized by their potent capacity to activate immunologically naive T cells. By subtracting the mRNAs expressed by the mouse epidermus-derived DC line XS52 with the mRNAs expressed by the J774 macrophage line, we identified five novel genes that were expressed selectively by this DC line. One of these genes encoded a type II...
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