Article
Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells.
Stem cells (Dayton, Ohio) - 1 May 2009
Senju Satoru, Haruta Miwa, Matsunaga Yusuke, Fukushima Satoshi, Ikeda Tokunori, Takahashi Kazutoshi, Okita Keisuke, Yamanaka Shinya, Nishimura Yasuharu
Abstract excerpt
Methods have been established to generate dendritic cells (DCs) from mouse and human embryonic stem (ES) cells. We designated them as ES-DCs and mouse models have demonstrated the induction of anti-cancer immunity and prevention of autoimmune disease by in vivo administration of genetically engineered ES-DCs. For the future clinical application of ES-DCs, the histoincompatibility between patients to be treated...
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