Article
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1993
Nestle F O, Zheng X G, Thompson C B, Turka L A, Nickoloff B J
Abstract excerpt
The relative contribution of dermal-derived immunocompetent cells to the overall immunologic response in skin has been hampered by the lack of appropriate isolation techniques. In this report, we provide a purification schema that reliably yields highly purified populations of dermal dendritic cells (DDC). These cells are motile, express high levels of class II MHC antigens that decorate their cytoplasmic...
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