Article
Long palindromic sequences induce double-strand breaks during meiosis in yeast.
Molecular and cellular biology - 1 May 2000
Nasar F, Jankowski C, Nag D K
Abstract excerpt
Inverted-repeated or palindromic sequences have been found to occur in both prokaryotic and eukaryotic genomes. Such repeated sequences are usually short and present at several functionally important regions in the genome. However, long palindromic sequences are rare and are a major source of genomic instability. The palindrome-mediated genomic instability is believed to be due to cruciform or hairpin formation...
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