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Article

Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 May 2000

McHugh P J, Sones W R, Hartley J A

Abstract excerpt

Bifunctional alkylating agents and other drugs which produce DNA interstrand cross-links (ICLs) are among the most effective antitumor agents in clinical use. In contrast to agents which produce bulky adducts on only one strand of the DNA, the cellular mechanisms which act to eliminate DNA ICLs are still poorly understood, although nucleotide excision repair is known to play a crucial role in an early repair...

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Identifiers

PMID: 10779332
DOI: 10.1128/MCB.20.10.3425-3433.2000
PMCID: PMC85635

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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