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Article

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.

Cell - 31 Mar 2000

Yamamoto A, Lucas J J, Hen R

Abstract excerpt

Neurodegenerative disorders like Huntington's disease (HD) are characterized by progressive and putative irreversible clinical and neuropathological symptoms, including neuronal protein aggregates. Conditional transgenic models of neurodegenerative diseases therefore could be a powerful means to explore the relationship between mutant protein expression and progression of the disease. We have created a...

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PMID: 10778856
DOI: 10.1016/S0092-8674(00)80623-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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