Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear mitogen-activated protein kinase activation by protein kinase czeta during reoxygenation after ischemic hypoxia.

The Journal of biological chemistry - 30 Jun 2000

Mizukami Y, Kobayashi S, Uberall F, Hellbert K, Kobayashi N, Yoshida K

Abstract excerpt

We examined the upstream kinases for mitogen-activated protein kinase (MAPK) activation during ischemic hypoxia and reoxygenation using H9c2 cells derived from rat cardiomyocytes. Protein kinase C (PKC)zeta, an atypical PKC isoform mainly expressed in rat heart, has been shown to act as an upstream kinase of MAPK during ischemic hypoxia and reoxygenation by analyses with PKC inhibitors, antisense DNA, a dominant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androstadienes
Share to Culture Media, Serum-Free

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinases

Share to Myocardial Ischemia

Share to Myocardial Reperfusion Injury

Share to Phosphoinositide-3 Kinase Inhibitors

Share to Protein Kinase C

Share to Wortmannin

Source

Identifiers

PMID: 10777509
DOI: 10.1074/jbc.M907901199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear mitogen-activated protein kinase activation by protein kinase czeta during reoxygenation after ischemic hypoxia.PMID 10777509Read ↗

Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia.Semantic proximity Read ↗

Molecular biology of protein kinase C signaling in cardiac myocytes.Semantic proximity Read ↗

Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes.Semantic proximity Read ↗

Differentiation of vascular smooth muscle cells and the regulation of protein kinase C-alpha.Semantic proximity Read ↗

Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.Semantic proximity Read ↗

Chronic Prenatal Hypoxia Induces Epigenetic Programming of PKCε Gene Repression in Rat HeartsSemantic proximity Read ↗

Nuclear localization of protein kinase C-alpha induces thyroid hormone receptor-alpha1 expression in the cardiomyocyte.Semantic proximity Read ↗

ZAK re-programs atrial natriuretic factor expression and induces hypertrophic growth in H9c2 cardiomyoblast cells.Semantic proximity Read ↗

Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element.Semantic proximity Read ↗

Protein kinase C-zeta overexpression induces erythroid phenotype in the monocytic leukaemia cell line U937.Semantic proximity Read ↗

Protein kinase Cepsilon-dependent MARCKS phosphorylation in neonatal and adult rat ventricular myocytes.Semantic proximity Read ↗

A potential role for protein kinase C-epsilon in regulating megakaryocytic lineage commitment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.