Article
Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes.
American journal of physiology. Heart and circulatory physiology - 1 Oct 2003
Heidkamp Maria C, Bayer Allison L, Scully Brian T, Eble Diane M, Samarel Allen M
Abstract excerpt
Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase critical for both cardiomyocyte survival and sarcomeric assembly during endothelin (ET)-induced cardiomyocyte hypertrophy. ET-induced FAK activation requires upstream activation of one or more isoenzymes of protein kinase C (PKC...
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