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Article

A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing.

The EMBO journal - 17 Apr 2000

Rutz B, Séraphin B

Abstract excerpt

The MSL5 gene, which codes for the splicing factor BBP/ScSF1, is essential in Saccharomyces cerevisiae, yet previous analyses failed to reveal a defect in assembly of (pre)-spliceosomes or in vitro splicing associated with its depletion. We generated 11 temperature-sensitive (ts) mutants and one cold-sensitive (cs) mutant in the corresponding gene and analyzed their phenotypes. While all mutants were blocked in...

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Identifiers

PMID: 10775271
DOI: 10.1093/emboj/19.8.1873
PMCID: PMC302019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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