Article
Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 1995
Sun Z W, Hampsey M
Abstract excerpt
Mutations in the Saccharomyces cerevisiae SSU71 gene were isolated as suppressors of a transcription factor TFIIB defect that confers both a cold-sensitive growth defect and a downstream shift in transcription start-site selection at the cyc1 locus. The ssu71-1 suppressor not only suppresses the...
Topics
- Amino Acid Sequence
- Genes, Fungal
- Genomic Library
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Restriction Mapping
- Saccharomyces cerevisiae
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Suppression, Genetic
- Transcription Factors
- Transcription Factors, TFII
- Transcription, Genetic