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Article

A systematic screen identifies Saf5 as a link between splicing and transcription in fission yeast.

PLoS genetics - 1 Jun 2024

Borao Sonia, Vega Montserrat, Boronat Susanna, Hidalgo Elena, Hümmer Stefan, Ayté José

Abstract excerpt

Splicing is an important step of gene expression regulation in eukaryotes, as there are many mRNA precursors that can be alternatively spliced in different tissues, at different cell cycle phases or under different external stimuli. We have developed several integrated fluorescence-based in vivo splicing reporter constructs that allow the quantification of fission yeast splicing in vivo on intact cells, and we...

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Identifiers

PMID: 38833506
DOI: 10.1371/journal.pgen.1011316
PMCID: PMC11178228

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