Article
Fine mapping of virus-neutralizing epitopes on hepatitis B virus PreS1.
Virology - 25 Apr 2000
Maeng C Y, Ryu C J, Gripon P, Guguen-Guillouzo C, Hong H J
Abstract excerpt
We identified the epitopes on the preS1 which induce antibodies that neutralize both ad and ay subtypes of hepatitis B virus (HBV). Previously we generated murine monoclonal antibodies KR359 and KR127 that bind specifically to the preS1 of HBV. In this study we have performed fine mappings of the epitopes of the antibodies by examining their reactivity with GST fusion proteins, which contain a series of deletion...
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