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Article

Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism.

Proceedings of the National Academy of Sciences of the United States of America - 29 May 2007

Chi Seung-Wook, Maeng Cheol-Young, Kim Seung Jun, Oh Mee Sook, Ryu Chun Jeih, Kim Sang Jick, Han Kyou-Hoon, Hong Hyo Jeong, Ryu Seong Eon

Abstract excerpt

The humanized monoclonal antibody HzKR127 recognizes the preS1 domain of the human hepatitis B virus surface proteins with a broadly neutralizing activity in vivo. We present the crystal structures of HzKR127 Fab and its complex with a major epitope peptide. In the complex structure, the bound pe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17517649
DOI: 10.1073/pnas.0701279104
PMCID: PMC1890477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17517649-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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