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Article

Alanine mutagenesis of high-mobility-group-protein-1 box B (HMG1-B).

The Biochemical journal - 1 May 2000

Taudte S, Xin H, Kallenbach N R

Abstract excerpt

We have generated a set of alanine-scanning substitutions in high-mobility-group protein 1 box B (HMG1-B; the second domain of the HMG1 nuclear protein from the rat) in order to explore the influence of specific surface side chains on its function and folding. Guanidine hydrochloride and thermal unfolding studies have been carried out to investigate the effect of substituted residues on the folding pathway....

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Identifiers

PMID: 10769186
PMCID: PMC1221019

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Source receipt: pubmed, retrieved 7 Sept 2026.

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