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Article

Folding of bovine pancreatic trypsin inhibitor (BPTI) variants in which almost half the residues are alanine.

Journal of molecular biology - 5 May 2000

Kuroda Y, Kim P S

Abstract excerpt

Recent studies indicate that a fraction of the information contained in an amino acid sequence may be sufficient for specifying a native protein structure. An earlier alanine-scanning experiment conducted on bovine pancreatic trypsin inhibitor (BPTI; 58 residues) suggested that if cumulative mutations have additive effects on protein stability, a native protein structure could be built from BPTI sequences that...

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Identifiers

PMID: 10772865
DOI: 10.1006/jmbi.2000.3622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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