Article
The Ataxia-telangiectasia mutated gene and breast cancer: gene expression profiles and sequence variants.
Cancer letters - 28 Sept 2005
Hall Janet
Abstract excerpt
The role of the Ataxia-telangiectaisa mutated (ATM) gene, as a risk factor for breast cancer has been a consistent theme in the literature since the first reports by Swift and colleagues who reported that ATM heterozygotes in AT families had increased risks of developing breast cancer. Loss of heterozygosity at the ATM locus has been reported in 30-40% of breast tumours and 50-70% show altered ATM protein levels....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.