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Article

Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse

1 Apr 2000

Abstract excerpt

Embryonic alkaline phosphatase (EAP) is expressed during the preimplantation period of mouse development; however, its function is unknown. To determine whether the absence of an EAP gene affects development of preimplantation embryos, we studied mice homozygous for the disrupted EAP gene (EAP.ko mice). Time to reach morphologically definedpreimplantation stages, preimplantation loss, cell count, gestation...

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Identifiers

PMID: 10767088
DOI: 10.1002/(sici)1097-0177(200004)217:4<440::aid-dvdy11>3.0.co;2-1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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