Article
Deadly decisions: the role of genes regulating programmed cell death in human preimplantation embryo development
27 Aug 2004
Abstract excerpt
Human preimplantation embryo development is prone to high rates of early embryo wastage, particularly under current in vitro culture conditions. There are many possible underlying causes for embryo demise, including DNA damage, poor embryo metabolism and the effect of suboptimal culture media, all of which could result in an imbalance in gene expression and the failed execution of basic embryonic decisions. In...
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