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Article

Construction and screening of Mycobacterium paratuberculosis insertional mutant libraries.

Archives of microbiology - 1 Mar 2000

Cavaignac S M, White S J, de Lisle G W, Collins D M

Abstract excerpt

Mycobacterium paratuberculosis causes Johne's disease, a common wasting disease in ruminants. As a first step in studying virulence mechanisms, libraries of random mutants were produced in two M. paratuberculosis strains by using the conditionally replicating shuttle phasmid phAE94 which contains the transposon Tn5367. Two thousand mutants were screened for auxotrophy, carbon source preference, and altered cell...

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Identifiers

PMID: 10763756
DOI: 10.1007/s002039900132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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