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Article

Generation and screening of a comprehensive Mycobacterium avium subsp. paratuberculosis transposon mutant bank.

Frontiers in cellular and infection microbiology - 1 Jan 2014

Rathnaiah Govardhan, Lamont Elise A, Harris N Beth, Fenton Robert J, Zinniel Denise K, Liu Xiaofei, Sotos Josh, Feng Zhengyu, Livneh-Kol Ayala, Shpigel Nahum Y, Czuprynski Charles J, Sreevatsan Srinand, Barletta Raúl G

Abstract excerpt

Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's Disease in ruminants. This enteritis has significant economic impact and worldwide distribution. Vaccination is one of the most cost effective infectious disease control measures. Unfortunately, current vaccines reduce clinical disease and shedding, but are of limited efficacy and do not provide long-term protective immunity....

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Biological Specimen Banks
DNA Transposable Elements
Macrophages
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Viability

Mutagenesis, Insertional

Mycobacterium avium subsp. paratuberculosis

Paratuberculosis

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Identifiers

PMID: 25360421
DOI: 10.3389/fcimb.2014.00144
PMCID: PMC4197770

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