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Article

IgG receptor IIa alleles determine susceptibility and severity of Guillain-Barré syndrome.

Neurology - 25 Apr 2000

van der Pol W L, van den Berg L H, Scheepers R H, van der Bom J G, van Doorn P A, van Koningsveld R, van den Broek M C, Wokke J H, van de Winkel J G

Abstract excerpt

OBJECTIVE: Guillain-Barré syndrome (GBS) is characterized by nerve infiltration of leukocytes and autoantibodies of the immunoglobulin G (IgG) isotype directed against nerve constituents. Leukocyte receptors for IgG (FcgammaR) constitute an important link between the humoral and cellular parts of the immune system and confer potent cellular effector functions to myelin-directed antibodies. Three FcgammaR...

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Identifiers

PMID: 10762510
DOI: 10.1212/wnl.54.8.1661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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