Article
Fc-gamma IIIa-V158F receptor polymorphism contributes to the severity of Guillain-Barré syndrome.
Annals of clinical and translational neurology - 1 Jun 2020
Hayat Shoma, Babu Golap, Das Avizit, Howlader Zakir Hossain, Mahmud Ishtiaq, Islam Zhahirul
Abstract excerpt
OBJECTIVE: Guillain-Barré syndrome (GBS) is a rare, life-threatening disorder of the peripheral nervous system. Immunoglobulin G Fc-gamma receptors (FcγRs) mediate and regulate diverse effector functions and are involved in the pathogenesis of GBS. We investigated whether the FcγR polymorphisms FcγRIIa H/R131 (rs1801274), FcγRIIIa V/F158 (rs396991), and FcγRIIIb NA1/NA2, and their haplotype patterns affect the...
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