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Article

Polymorphisms of Immunoglobulin G Fc Receptors in Pediatric Guillain-Barré Syndrome.

Neuropediatrics - 1 Jun 2016

Mansour Lobna A, Girgis Marian Y, Abdulhay Mohamed, ElEinein Ehab I Abou, ElHawary Rabab, Hanna Mariam Onsy F

Abstract excerpt

Introduction Guillain-Barré syndrome (GBS) is an autoimmune peripheral neuropathy characterized by demyelination and axonal damage. Biallelic functional polymorphisms in the immunoglobulin G Fc receptors (FcγR)-FcγRIIA: H131/R131, FcγRIIIA: V158/F158, and FcγRIIIB: NA1/NA2 affect the affinity of the IgG-FcγR interaction, therefore, diseases such as GBS in which this interaction plays a critical role might be...

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PMID: 27064330
DOI: 10.1055/s-0036-1579633

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