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Article

Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Journal of virology - 1 Feb 1990

Melvold R W, Jokinen D M, Miller S D, Dal Canto M C, Lipton H L

Abstract excerpt

Theiler's virus-induced demyelinating disease results from a chronic infection in the white matter of the central nervous system and provides an excellent model for human multiple sclerosis. Like multiple sclerosis, there are genetic risk factors in disease development, including genes associated with the major histocompatibility complex and with those encoding the beta chain of the T-cell receptor. Comparisons...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Demyelinating Diseases
Disease Susceptibility
Encephalomyelitis
Enterovirus Infections
Genotype
Haplotypes
Maus Elberfeld virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred Strains

Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 2296080
DOI: 10.1128/JVI.64.2.686-690.1990
PMCID: PMC249161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2296080-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.PMID 2296080Read ↗

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