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Article

Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures.

The Journal of experimental medicine - 20 Jan 1997

Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, Zimmermann V S, Davoust J, Ricciardi-Castagnoli P

Abstract excerpt

The signals controlling the checkpoints of dendritic cells (DC) maturation and the correlation between phenotypical and functional maturational stages were investigated in a defined model system of growth factor-dependent immature mouse DC. Three sequential stages of DC maturation (immature, mature, and apoptotic) were defined and characterized. Immature DC (stage 1) had low expression of costimulatory molecules,...

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Identifiers

PMID: 9016880
DOI: 10.1084/jem.185.2.317
PMCID: PMC2196118

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Source receipt: pubmed, retrieved 7 Sept 2026.

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