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Article

Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition.

Journal of molecular and cellular cardiology - 1 Apr 2000

Lim H W, De Windt L J, Mante J, Kimball T R, Witt S A, Sussman M A, Molkentin J D

Abstract excerpt

Heart disease remains one of the leading causes of morbidity and mortality in the industrialized nations of the world. Intense investigation has centered around identifying and manipulating intracellular signaling pathways that direct hypertrophic and myopathic responses in an attempt to intervene in the progression or reverse certain forms of heart disease. We show here that cyclosporin A-mediated inhibition of...

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Identifiers

PMID: 10756124
DOI: 10.1006/jmcc.2000.1113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition.PMID 10756124Read ↗

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