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Autophagy proteins in antigen processing for presentation on <scp>MHC</scp> molecules

20 Jun 2016

Abstract excerpt

Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC) molecules sample protein degradation products and present them to T cells for adaptive immunity, it is maybe not too surprising that autophagy contributes to this protein antigen processing for MHC presentation. However, the recently recognized breath of pathways, by...

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PMID: 27319339
DOI: 10.1111/imr.12422

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