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Article

Salmonella pathogenesis reveals that BMP signaling regulates blood cell homeostasis and immune responses in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 2008

Frandsen Joel L, Gunn Bronwyn, Muratoglu Selen, Fossett Nancy, Newfeld Stuart J

Abstract excerpt

Intercellular signaling by bone morphogenetic proteins (BMPs) regulates developmental decisions in virtually all animals. Here, we report that Decapentaplegic (Dpp; a Drosophila BMP family member) plays a role in blood cell homeostasis and immune responses by regulating a transcription factor cascade. The cascade begins with Dpp repression of Zfh1, continues with Zfh1 activation of Serpent (Srp; a GATA factor),...

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Identifiers

PMID: 18815369
DOI: 10.1073/pnas.0808208105
PMCID: PMC2553038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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