Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant-specific gene programs in the zebrafish.

Blood - 15 Jul 2005

Weber Gerhard J, Choe Sung E, Dooley Kimberly A, Paffett-Lugassy Noëlle N, Zhou Yi, Zon Leonard I

Abstract excerpt

Hematopoiesis involves the production of stem cells, followed by the orchestrated differentiation of the blood lineages. Genetic screens in zebrafish have identified mutants with defects that disrupt specific stages of hematopoiesis and vasculogenesis, including the cloche, spadetail (tbx16), moonshine (tif1g), bloodless, and vlad tepes (gata1) mutants. To better characterize the blood program, gene expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Vessels
Share to Erythropoiesis
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoiesis

Share to In Situ Hybridization

Share to Multigene Family

Share to Myelopoiesis

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 15827125
DOI: 10.1182/blood-2004-11-4541
PMCID: PMC1895186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant-specific gene programs in the zebrafish.PMID 15827125Read ↗

The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.Semantic proximity Read ↗

Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants.Semantic proximity Read ↗

Use of the zebrafish system to study primitive and definitive hematopoiesis.Semantic proximity Read ↗

Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes.Semantic proximity Read ↗

Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos.Semantic proximity Read ↗

A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes.Semantic proximity Read ↗

Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification.Semantic proximity Read ↗

Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish.Semantic proximity Read ↗

Zebrafish: a genetic approach in studying hematopoiesis.Semantic proximity Read ↗

Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish.Semantic proximity Read ↗

Characterization of zebrafish mutants with defects in embryonic hematopoiesis.Semantic proximity Read ↗

<i>rapunzel5</i> is necessary for normal hematopoietic development in zebrafishSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.