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Article

Role of TNF-α polymorphism -308 in neurosensory irritation.

International journal of cosmetic science - 1 Apr 2011

Davis J A, Visscher M O, Wickett R R, Hoath S B

Abstract excerpt

Neurosensory cutaneous discomfort in response to topical products is common, yet the relationship between symptoms such as stinging and visible irritation is currently unclear. The presence of a polymorphism at position -308 on the TNF-α gene has been associated with skin irritation, i.e., erythema, dryness. Individuals with a G to A transition (AA/GA genotypes) have a lower threshold to experimentally induced...

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Source

Identifiers

PMID: 20646084
DOI: 10.1111/j.1468-2494.2010.00597.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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