Article
[Study on the p53 gene mutation and microsatellite instability of gastric carcinoma].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2000
Guo W, Zhang Y, Wu B, Zhang L, Zhou D
Abstract excerpt
OBJECTIVE: To observe the relationship between p53 gene mutation and microsatellite instability (MSI) of the preoperative staging of gastric carcinoma by endoscopic ultrasonography(EUS). METHODS: A total of 73 cases of gastric carcinoma were taken for the preoperative staging with EUS. Silver staining PCR-SSCP method was used to detect mutations in exons 5, 6, 7, 8 of p53 gene and MSI at 4 loci on chromosomes 2,...
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