Article
Association of Intron Microsatellite Instability and Exon Mutational Profile of TP53 in Human Gastric Cancers.
Anticancer research - 1 Aug 2017
Huo Xueyun, Xiao Xiaoqin, Zhang Shuangyue, Zhou Deshan, Chen Zhenwen
Abstract excerpt
BACKGROUND/AIM: Microsatellite instability (MSI) is a hallmark of genomic instability. In gastric cancer (GC), MSI phenotype is an important molecular subgroup that is often closely correlated with elevated mutation rates on the whole genome level. However, on a single gene level, it is still unknown whether the MSI status of a gene is correlated with the mutational profile of the gene itself. MATERIALS AND...
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